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Label Reading

The Arithmetic Of A 500 mg Blend Split Fourteen Ways

This takes five minutes and a calculator, and it tells you more about a supplement than every review on the internet put together.

  • Published 14 April 2026
  • 9 min read
  • Filed under Label Reading

Short Version

Add up the research doses of everything in a blend. If that total is bigger than the blend weight, at least some ingredients are below their studied amounts — and the ones listed last are furthest below. This is arithmetic, not opinion, and it works on any label.

What A Proprietary Blend Is Allowed To Hide

US supplement labelling rules require three things of a blend. Every ingredient must be named. They must be listed in descending order by weight. And the total weight of the blend must be accurate.

What is not required is an individual figure for each name. That is the whole gap, and it is entirely legal. The stated justification is trade secrecy — a competitor could copy a formula from exact ratios.

The practical consequence is that a panel can be completely honest and completely uninformative at the same time. Fourteen names, one number, and no way to know from outside the factory how that number is divided.

The Method, In Four Steps

  1. Write down the blend weight. It is on the panel, immediately after the blend name. For GlycoAid it is 500 mg.
  2. Look up the research dose for each ingredient. The NIH fact sheets and NCCIH pages carry these for most common names, and every ingredient page on this site states one.
  3. Compare each dose against the blend total. Any ingredient whose research dose is bigger than the whole blend cannot possibly be at that dose. No arrangement of the other thirteen changes that.
  4. Read the ordering. Descending by weight is the one piece of dose information you actually get. Whatever is listed first has more in it than whatever is listed last.

Worked Through On This Label

Here is that method applied to the fourteen names in GlycoAid, using the doses the published human trials actually used.

IngredientTrial doseCan it fit in 500 mg?
Berberine900–1,500 mg dailyNo. Needs two to three times the whole blend
Alpha-lipoic acid600 mg dailyNo. More than the whole blend
Bitter melon2,000–3,000 mgNo. Four to six times over
Cinnamon1,000–6,000 mgNo. Twice over at best
Maca root1,500–3,000 mgNo. Three to six times over
Turmeric extract500–1,500 mgNo. The whole blend at best
Gymnema extract200–400 mgPossible, if it took most of the blend
White mulberry200–1,000 mgPossible at the low end
Goji polysaccharide150–300 mgPossible at the low end
Banaba leaf32–48 mg standardisedYes, comfortably — under a tenth of the blend
Chromium200 microgramsYes. 0.04% of the blend by weight
Biotin30 micrograms adequate intakeYes. 0.006% by weight
Juniper berryNo established human doseNothing to compare against
Licorice rootNo established glucose doseSafety limit rather than an effective dose

Add the six "no" rows together. Berberine at 900, ALA at 600, bitter melon at 2,000, cinnamon at 1,000, maca at 1,500 and turmeric at 500 comes to 6,500 mg — thirteen times the blend, using the lowest figure in every range. That is the size of the gap, and no reformulation closes it.

What The Answer Actually Means

Not that the product is a fraud. It means the product is a different thing from what most buyers assume they are getting, and that distinction is worth understanding before you pay.

  • Micronutrients are unaffected. Chromium and biotin are measured in micrograms and take up no meaningful room. They can be at any amount the maker chose.
  • A few botanicals genuinely fit. Banaba Leaf at 32 to 48 mg is comfortably deliverable, which makes it one of the more interesting names on a label like this.
  • The famous ones cannot. Berberine is the name most people are buying for and the one the arithmetic treats most harshly.
  • Ordering is your only other clue. Read the list order. It is the one dose signal a blend gives you.

Three Things This Does Not Prove

Fairness requires these.

First, an under-dosed ingredient is not necessarily a useless one. Effects are not all-or-nothing, and a fraction of a dose may produce a fraction of an effect. It just will not produce the trial result.

Second, combinations are not always additive. It is at least possible that several small amounts do something a single ingredient would not. That is a hypothesis rather than a finding, and no blend has demonstrated it.

Third, this problem is close to universal. Nearly every multi-botanical supplement sold has it, and a 500 mg blend of fourteen names is unremarkable in this market. Singling out one product for something the whole category does would be dishonest.

What To Do With The Answer

Buy with the right expectation, or buy something else.

If you want a specific ingredient at a researched dose, buy that ingredient on its own. A standalone product declares its amount, and you can check it against the literature in a minute.

If you want a broad daily botanical with two nutritional amounts you can verify, a blend is a perfectly reasonable thing to buy — provided nobody has told you it is the other thing. That is the whole point of running the arithmetic first.

Questions On This Article

What readers ask after reading it.

Are proprietary blends legal?

Yes. US rules require every ingredient to be named, listed heaviest first, and the blend total to be accurate. They do not require an individual figure for each name.

Why do companies use them?

The stated reason is trade secrecy, so a competitor cannot copy exact ratios. The practical effect is that buyers cannot check doses.

Does the ingredient order really mean anything?

Yes, and it is the one dose signal you get. Ingredients must be listed in descending order by weight, so what appears first has more in it than what appears last.

Is an under-dosed ingredient useless?

Not necessarily. Effects are rarely all-or-nothing, so a fraction of a dose may produce a fraction of an effect. It will not reproduce the trial result.

Do vitamins and minerals have to be declared separately?

Vitamins and minerals carry percent daily values even inside a blend, which is why chromium and biotin are the two checkable figures on this particular label.

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